Genetic Diversity of South Asia

South Asia is a culturally, linguistically and genetically complex region of the world, and one of the first regions to be reach by anatomically modern humans after leaving Africa some 70,000 years ago.

For purposes of analysis, we consider South Asia to consist of Afghanistan, Pakistan, India, Bangladesh, Nepal and Bhutan (see map below).

A Map of South Asia

Image Source: Library of Congress Geography and Map Division

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Nepal

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Publications

Arunkumar G, Soria-Hernanz DF, Kavitha VJ, Arun VS, Syama A, Ashokan KS, Gandhirajan KT, Vijayakumar K, Narayanan M, Jayalakshmi M, Ziegle JS, Royuru AK, Parida L, Wells RS, Renfrew C, Schurr TG, Smith CT, Platt DS, Pitchappan R, The Genographic Consortium. 2012. Population differentiation of southern Indian male lineages correlates with agricultural expansions predating the caste system. PLoS ONE 7(11): e50269.

Haber M, Platt DE, Bonab MA, Youhanna SC, Soria-Hernanz DF, Martínez-Cruz B, Douayhi B, Ghassibe-Sabbagh M, Rafatpanah H, Ghanbari M, Balanovsky O, Wells RS, Comas D, Tyler-Smith C, Zalloua PA, The Genographic Consortium. 2012. Afghanistan’s ethnic groups share a Y-chromosomal heritage structured by historical events. PLoS ONE 7(3): e34288.

ArunKumar GP, Hai L Kavitha VJ, Syama A, Arun VS, Sahoo S, Patel S, Sathwa SK, Balakrishnan R, Riba T, Chakravarthy J, Chaudhury B, Panda P, Das PK, Nyak PK, Li H, Pitchappan R, The Genographic Consortium. 2015. A late Neolithic expansion of Y chromosomal haplogroup O2a1-M95 from east to west. J Syst Evol Article first published online: 31 Mar 2015 doi:10.1111/jse.12147.

ArunKumar G, Tatarinova TV, Duty J, Rollo D, Syama A, Arun VS, Kavitha VJ, Triska P, Greenspan B, Wells RS, Pitchappan R, The Genographic Consortium. 2015. Genome-wide signatures of male-mediated migration shaping the Indian gene pool. J Hum Genet 60(9): 493-499.

Syama A, Arun VS, Arunkumar G, Subhadheepta R, Kai F, Pitchappan RM, The Genographic Consortium. 2019. Origin and identity of the Brokpa of Dah-Hanu, Himalayas – An NRY-HG L1a2 (M357) legacy. Ann Hum Biol 46(7-8): 562-573.

Zubair M, Habib A, Hemphill BE, Schurr TG, Tariq M. 2020. Mitochondrial genetic diversity of the Khattak and Kheshgi tribes of Peshawar Valley, Pakistan. Genetica 148: 195-206

Tariq M, Habib A, Hemphill BE, Farooq U, Schurr TG. 2022. Contrasting maternal and paternal genetic histories of five major ethnic groups of Khyber Pakhtunkhwa, Pakistan. Nature Scientific Reports 12: 1027.

Laboratory of Molecular Anthropology
University of Pennsylvania
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