mtDNA Variation and Aging
Overview of the role of the mitochondrion in the aging process, and various theories about the evolution of senescence.
Discuss looking for genetic influences on longevity in human populations, including telomerase. Seeking more comprehensive explanation for process of aging in humans, and other organisms by extension.
A summary of the effects of aging on mitochondrial OXPHOS function. Source: Cedikova et al. 2016. Multiple roles of mitochondria in the aging process. Physiol. Res. (Suppl. 5): S519-S531.
Description of collaboration with Astanand Jugessur NIPH and others.
The Norwegian Mother, Father and Child Cohort Study (MoBa) is a study of the causes of disease among mothers and children. MoBa began to recruit pregnant women in 1999. Fathers were also invited. In 2008, the goal of more than 100 000 pregnancies was reached. Biological material and questionnaire data have been collected since the 17th week of pregnancy which makes the study unique.
mtDNA Variation and Aging in Norway
Logo for the Norwegian Mother, Father and Child Cohort Study (MoBa). Source: https://blog.norwegianreward.com/en/lifestyle/norway-constitution-day/
Laboratory of Molecular Anthropology
University of Pennsylvania
421 University Museum
3260 South Street
Philadelphia, PA 19104-6398
Tel: 215-573-2656
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